4b-R= CH20H 10 to study this solvent effect in other solvents because of the low solubilities of the imidazoles. In an attempt to establish the structure of these pairs of constitutional isomers, we examined their proton magnetic resonance spectra; but the evidence was inconclusive. Methods for distinguishing between 1, 4-and 1, Bdisubstituted imidazoles by cross-ring coupling constants, l use of lanthanide shift reagents? and carbon-13 chemical ...