A positional isomer of trimetoquinol (l), 1-(2', 4', 5'-trimethoxybenzyl)-6, 7-dihydroxy-l, 2, 3, 4- tetrahydroisoquinoline (3), was synthesized and found to possess less &adrenergic activity than 1 in isolated guinea pig atrial and tracheal preparations. The analogue 3 was an effective antiaggregatory agent in human and rabbit platelet-rich plasma preparations, while 1 was effective only as an inhibitor of arachidonic acid induced aggregation in human ...
![1-[(2,4,5-trimethoxyphenyl)methyl]-1,2,3,4-tetrahydroisoquinoline-6,7-diol,hydrochloride结构式](https://image.chemsrc.com/caspic/098/72943-42-1.png)
![(1R)-1-((3aR,5R,6aR)-6-(benzyloxy)-2,2,6-trimethyltetrahydrofuro[2,3-d][1,3]dioxol-5-yl)ethane-1,2-diol结构式](https://image.chemsrc.com/caspic/010/55536-65-7.png)
![N-[[3,4-(dibenzyloxy)phenyl]ethyl]-2',4',5'-trimethoxyphenylacetamide结构式](https://image.chemsrc.com/caspic/077/72943-38-5.png)
