Helvetica chimica acta

The CAMET and CASET links for the synthesis of protected oligopeptides and oligodeoxynucleotides on solid and soluble supports

R Schwyzer, E Felder, P Merli??Failli

文献索引：Schwyzer, Robert; Felder, Eduard; Failli, Paola Helvetica Chimica Acta, 1984 , vol. 67, p. 1316 - 1327

全文：HTML全文

被引用次数: 24

摘要

Abstract Simple bifunctional carboxy-and phospho-protecting groups are described which allow the attachment of protected amino acids and nucleotides to soluble or insoluble carriers. After chemical synthesis with conventional procedures, the completed oligopeptides or oligonucleotides can be detached by base-catalyzed β-elimination, leaving other protecting groups intact. These protected biopolymer segments can then be purified, ...