Carbohydrate research

Synthesis of heterocyclic N-(β-d-glucopyranosyl) carboxamides for inhibition of glycogen phosphorylase

B Kónya, T Docsa, P Gergely, L Somsák

文献索引：Konya, Balint; Docsa, Tibor; Gergely, Pal; Somsak, Laszlo Carbohydrate Research, 2012 , vol. 351, p. 56 - 63

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被引用次数: 17

摘要

In a DCC-mediated coupling 2, 3, 4, 6-tetra-O-acetyl-β-d-glucopyranosylamine and propiolic acid gave N-propynoyl-2, 3, 4, 6-tetra-O-acetyl-β-d-glucopyranosylamine which was transformed by 1, 3-dipolar cycloadditions with aromatic azides and nitrile-oxides to the corresponding O-peracetylated N-(β-d-glucopyranosyl)-1-substituted-1, 2, 3-triazole-4- carboxamides and N-(β-d-glucopyranosyl)-3-substituted-isoxazole-5-carboxamides, ...