IN developing new methods for the regiospecific synthesis of substituted indoles,l we were interested in the possi- bility of using the chromium tricarbonyl unit to activate the aryl ring of this fused heterocycle to nucleophilic sub- stitution. The synthetic potential of the powerful electron withdrawing effect of this group 6~ element was first suggested by Trahanovsky and Card. Additional studies by Semmelhack and his co-workers have elaborated on the synthetic scope and mechanistic ...
