Application of chlorotrimethylsilane in Pictet–Spengler reaction

…, AS Plaskon, AA Tolmachev, RV Smaliy

文献索引：Ryabukhin, Sergey V.; Panov, Dmitriy M.; Plaskon, Andrey S.; Tolmachev, Andrey A.; Smaliy, Radomyr V. Monatshefte fur Chemie, 2012 , vol. 143, # 11 p. 1507 - 1517

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被引用次数: 7

摘要

Abstract Chlorotrimethylsilane has been found to be an efficient condensing agent in the Pictet–Spengler reaction, affording an extremely straightforward synthetic route to tetrahydro- β-carboline derivatives and their analogs. The applicability of the method has been studied, and a representative library of structurally diverse products has been created. Graphical Abstract.