Synthesis of gem??Difluoromethylenated Spiro?螃摸?butyrolactones by Employing PhSCF2Si (CH3) 3 as a gem??Difluoromethylenating Agent

…, D Soorukram, C Kuhakarn, P Tuchinda…

文献索引：Chatupheeraphat, Adisak; Soorukram, Darunee; Kuhakarn, Chutima; Tuchinda, Patoomratana; Reutrakul, Vichai; Pakawatchai, Chaveng; Saithong, Saowanit; Pohmakotr, Manat European Journal of Organic Chemistry, 2013 , # 30 p. 6844 - 6858

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被引用次数: 5

摘要

Abstract PhSCF 2 TMS was utilized as a useful gem-difluoromethylene building block for the synthesis of gem-difluoromethylenated spiro-γ-butyrolactones. The radical cyclization of γ- alkenyl-γ-gem-difluoro (phenylsulfanyl) methyl-γ-butyrolactones provided gem- difluoromethylenated spiro-γ-butyrolactones.