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Blue fluorescent deoxycytidine analogues: convergent synthesis, solid-state and electronic structure, and solvatochromism

DW Dodd, KN Swanick, JT Price, AL Brazeau…

文献索引:Dodd, David W.; Swanick, Kalen N.; Price, Jacquelyn T.; Brazeau, Allison L.; Ferguson; Jones, Nathan D.; Hudson, Robert H. E. Organic and Biomolecular Chemistry, 2010 , vol. 8, # 3 p. 663 - 666

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被引用次数: 33

摘要

We report the synthesis and photospectroscopic characterisation of intrinsically fluorescent triazole-appended cytidines. Fluorescence was found to be highly dependent on solvent conditions. X-Ray crystallographic data show the proton of the exocyclic amine of the nucleobase and the triazole N3 engaged in a H-bond.