Tetrahedron

Synthesis of some acridone alkaloids and related compounds

JJ Chen, LW Deady, MF Mackay

文献索引：Chen, Jun-Jie; Deady, Leslie W.; Mackay, Maureen F. Tetrahedron, 1997 , vol. 53, # 37 p. 12717 - 12728

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被引用次数: 21

摘要

An efficient Pd/C aromatization of 1, 2, 3, 4, 9, 10-hexahydroacridine-1, 9-diones to 1- hydroxyacridones is reported. The previously reported four-step synthesis of the diones has been extended to give a number of methoxy substituted derivatives and the aromatization reaction, along with hydrobromic acid demethylation, provides a useful route to various methoxy and hydroxy substituted acridones.