Synthesis and biological activity of [7-amino-s-triazole [1, 5-c] pyrmididyl-5]-thioacetic acid derivatives

…, GM Anoshina, VI Il'enko, GG Vatulina

文献索引：Dianova, L. N.; Koksharova, T. G.; Volkova, N. V.; Anoshina, G. M.; Il'enko, V. I,; Vatulina, G. G. Pharmaceutical Chemistry Journal, 1992 , vol. 26, # 2 p. 134 - 137 Khimiko-Farmatsevticheskii Zhurnal, 1992 , vol. 26, # 2 p. 30 - 32

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摘要

The s-triazole [l, 5-c] pyri~ idines constitute a limited and relatively little-studied class of compounds. Nevertheless, substances have been found among them that display a broad range of pharmacological activity, including bronchodilating [4], sedative, hypotensire [6], anti-inflammatory, and analgesic [5, 6] properties. This makes the synthesis and search for new biologically-active substances in the s-triazole [l, 5-c] pyrimidine series particularly ...