Synthetic communications

Solvent??free synthesis of 1, 5??benzothiazepines and benzodiazepines on inorganic supports

M Kodomari, T Noguchi, T Aoyama

文献索引：Kodomari, Mitsuo; Noguchi, Tomohiro; Aoyama, Tadashi Synthetic Communications, 2004 , vol. 34, # 10 p. 1783 - 1790

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被引用次数: 52

摘要

Abstract 1, 5??Benzothiazepines and 1, 5??benzodiazepines have been synthesized in solvent??free conditions from chalcones and o??aminothiophenol or o??phenylenediamine in the presence of inorganic support. Silica gel was found to be an effective support for the synthesis of 1, 5??benzothiazepines, whereas alumina was effective for the synthesis of 1, 5?? benzodiazepines.