前往化源商城

Synthesis of tris-hydroxymethyl-based nitrone derivatives with highly reactive nitronyl carbon

F Choteau, B Tuccio, FA Villamena…

文献索引:Choteau, Fanny; Tuccio, Beatrice; Villamena, Frederick A.; Charles, Laurence; Pucci, Bernard; Durand, Gregory Journal of Organic Chemistry, 2012 , vol. 77, # 2 p. 938 - 948

全文:HTML全文

被引用次数: 4

摘要

A novel series of α-phenyl-N-tert-butyl nitrone derivatives, bearing a hydrophobic chain on the aromatic ring and three hydroxyl functions on the tert-butyl group, was synthesized through a short and convenient synthetic route based on a one-pot reduction/condensation of tris (hydroxymethyl) nitromethane with a benzaldehyde derivative. Because of the presence of hydroxyl functions on the tert-butyl group, an intramolecular Forrester– ...