Etude de la réaction de cyclisation des halohydrines-1, 2 ethyl phosphonates de diéthyle pour l'obtention de l'époxy-1, 2 éthyl phosphonate de diéthyle

G Sturtz, A Pondaven-Raphalen

文献索引：Sturtz, G.; Pondaven-Raphalen, A. Phosphorus and Sulfur and the Related Elements, 1984 , vol. 20, p. 35 - 48

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被引用次数: 10

摘要

Abstract Here we report on the synthesis of the diethyl 1, 2-epoxyethylphosphonate 1 from diethyl 1-halogeno 2-hydroxyethylphosphonates 4a and 4b. The halohydrins were prepared by hypohalogenation of the diethyl vinylphosphonate and their structures confirmed by 31P. 1H and 13C NMR spectroscopy. The epoxidation cyclisation was studied using a variety of bases (HNa. KOH, EtO−, K2CO3) and solvents (THF, EtOH, MeOH). In aprotic solvents, ...