Conversion of aryl methyl ketimines to 2, 5-diarylpyrroles using TiCl4/Et3N

M Periasamy, G Srinivas, P Bharathi

文献索引：Periasamy, Mariappan; Srinivas, Gadthula; Bharathi, Pandi Journal of Organic Chemistry, 1999 , vol. 64, # 11 p. 4204 - 4205

全文：HTML全文

被引用次数: 106

摘要

The 2, 5-diarylpyrroles are generally synthesized by following the classical PaalrKnorr synthesis involving the reaction of 1, 4-diketone with amines. 1 Some of the shortcomings in this reaction were overcome by a later method reported by McEwen. 2 Other methods available for pyrrole synthesis are Hantzsch synthesis using chloroacetone and 3-amino ethyl crotonate, 3 1, 3-dipolar cycloaddition reactions involving azalactones, oxazolones, ...