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Synthesis of novel indolizine derivatives

B Bonnaud, D Bigg, JF Patoiseau

文献索引:Bonnaud, Bernard; Bigg, Dennis; Patoiseau, Jean-Francois Journal of Heterocyclic Chemistry, 1991 , vol. 28, # 8 p. 1927 - 1932

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被引用次数: 2

摘要

Abstract The reaction of a number of γ-butyrolactones with azole anions is shown to give γ- substituted butanoic acids in moderate to good yields. The pyrrolyl and indolylbutanoic acids obtained underwent cyclization in a simple one-pot procedure employing ethyl chloroformate and boron trifluoride etherate. Some aspects of the chemistry of the resulting indolizin-8-ones are described.