Synthesis and antihepatotoxicity of some Wuweizisu analogues

…, SE Chen, WL Chang, CF Chen, AR Lee

文献索引：Wu; Chen; Chang; Lee European Journal of Medicinal Chemistry, 1992 , vol. 27, # 4 p. 353 - 358

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被引用次数: 18

摘要

Abstract A preparation of dimethyl 4, 4′-dimethoxy-5, 6, 5′, 6′-dimethylenedioxybiphenyl- 2, 2′-dicarboxylate (VII) was readily achieved. It provided the advantages of specificity, simplicity, and efficiency in reactions. 6-Phenyl-3, 9-dimethoxy-1, 2-methylenedioxy-10, 11- methylenedioxy-6, 7-dihydro-5H-dibenz (c, e) azepin (X) was successfully synthesized from VII (DDB) and its liver-protective property proved to be more effective than DDB and ...