Highly Regioselective α??Arylation of Coumarins via Palladium??Catalyzed C H Activation/Desulfitative Coupling

F Jafarpour, MBA Olia, H Hazrati

文献索引：Jafarpour, Farnaz; Olia, Mina Barzegar Amiri; Hazrati, Hamideh Advanced Synthesis and Catalysis, 2013 , vol. 355, # 17 p. 3407 - 3412

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被引用次数: 35

摘要

Abstract: A novel regioselective α-arylation of coumarins with readily available arenesulfonyl chlorides and sodium arenesulfinates via palladium-catalyzed direct CÀH functionalizations under mild reaction conditions is described. This protocol presents an unexpected and highly regio-controlled arylation of coumarins at C-3 to construct interesting 3-arylcoumarins with fascinating biological and fluorescent properties. The regioselectivity observed is in ...