Preparation of N-Boc N-alkyl glycines for peptoid synthesis

AM Mouna, C Nguyen, I Rage, J Xie, G Nee…

文献索引：Mouna; Nguyen; Rage; Xie; Nee; Mazaleyrat; Wakselman Synthetic Communications, 1994 , vol. 24, # 17 p. 2429 - 2435

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被引用次数: 24

摘要

Abstract A series of N-tert-butoxycarbonylated N-allyl, N-propargyl, N-benzyl or branched N- alkyl glycines, useful building blocks for the synthesis of N-alkyl glycine oligomers, have been prepared by N-alkylation of N-Boc glycine or by a two-step method: reductive alkylation and tert-butoxycarbonylation.