Convenient and simplified approaches to N-monoprotected triaminopropane derivatives: Key intermediates for bifunctional chelating agent synthesis

E Benoist, A Loussouarn, P Remaud, JF Chatal…

文献索引：Benoist, Eric; Loussouarn, Anthony; Remaud, Patricia; Chatal, Jean-Francois; Gestin, Jean-Francois Synthesis, 1998 , # 8 p. 1113 - 1118

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被引用次数: 23

摘要

Abstract: High yields of selectively N-protected-1, 2, 3-triaminopropanes (1, 3 or 1, 2 functionalized diamines) were obtained in 6 or 4 steps from diamino alcohols or aminodiols, respectively. These two multi-step procedures involve protection of the amino group, substitution of the hydroxy group by an azido group and selective reduction. The conditions for the first procedure allow the preparation of various N2-monoprotected-1, 2, 3- ...