Tetrahedron letters

Synthesis of pyrrolo [1, 2-a] indoles by intramolecular Heck reaction of N-(2-bromoaryl) enaminones

JP Michael, SF Chang, C Wilson

文献索引：Michael, Joseph P.; Chang, Shih-Fang; Wilson, Clare Tetrahedron Letters, 1993 , vol. 34, # 51 p. 8365 - 8368

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被引用次数: 50

摘要

Abstract Treatment of N-(2-bromoaryl) enaminones 4, prepared by several different methods, with palladium (II) acetate, triarylphosphine and triethylamine in boiling acetonitrile gave pyrrolo [1, 2-a] indoles 8 yields of 50%–100%. The hydroxy-substituted products 8k could be oxidised to the mitosene-like quinone 9 with Fremy's salt.