SYNTHESIS AND ANTICHOLINESTERASE ACTIVITY OF SOME OXAZAPHOSPHOLINE AND BENZO-1, 3, 2-DIOXAPHOSPHOLENE, DIAZAPHOSPHOLINE 2-ONES …

HM Ali

文献索引：Ali, Hussein M. Phosphorus, Sulfur and Silicon and Related Elements, 1999 , vol. 155, p. 157 - 166

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被引用次数: 6

摘要

Abstract Synthesis of the titled compounds has been described. 1H NMR, IR band frequencies and MS fragmentation and rearrangement peaks were analyzed and discussed in detail. Studying the inhibitory effect of these compounds on acetylcholinesterase (AChE) showed that dioxaphospholenes were stronger inhibitors than oxazaphospholines and diazaphospholines. This was explained by increasing the number of nitrogen atoms ...