Stability of 1∶ 1 and 2∶ 1 α-cyclodextrin–p-nitrophenyl acetate complexes and the effect of α-cyclodextrin on acyl transfer to peroxide anion nucleophiles

D áMartin Davies, ME Deary

文献索引：Davies, D. Martin; Deary, Michael E. Journal of the Chemical Society. Perkin Transactions 2, 1999 , # 5 p. 1027 - 1034

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被引用次数: 10

摘要

The presence of a rate maximum rather than simple saturation-type kinetics in a study of the effect of α-cyclodextrin on the hydrolysis of p-nitrophenyl acetate (PNPA) indicates that α- cyclodextrin forms not only 1∶ 1 but also 2∶ 1 complexes with PNPA. This is confirmed using a spectrophotometric method to determine binding constants directly for PNPA, giving values of 46±9 and 66±19 dm3 mol–1 for the first and second binding steps respectively. ...