Molecules

Effects of Chirality on the Antifungal Potency of Methylated Succinimides Obtained by Aspergillus fumigatus Biotransformations. Comparison with Racemic …

M Sortino, A Postigo, S Zacchino

文献索引：Sortino, Maximiliano; Postigo, Agustina; Zacchino, Susana Molecules, 2013 , vol. 18, # 5 p. 5669 - 5683

全文：HTML全文

被引用次数: 6

摘要

Abstract: Eighteen (3 R) and (3 R, 4 R)-N-phenyl-, N-phenylalkyl and N-arylsuccinimides were prepared with high enantioselectivity by biotransformation of maleimides with A. fumigatus. This environmentally friendly, clean and economical procedure was performed by the whole-cell fungal bioconversion methodology. Their corresponding eighteen racemic succinimides were prepared instead by synthetic methods. Both, the racemic and the ...