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Recherches sur la formation et la transformation des esters LXXII. Aryl (ou aralcoyl ou alcoyl) amino??2??tétrahydro??m??thiazines ou aryl (ou aralcoyl ou alcoyl) amino??2 …

E Cherbuliez, B Baehler, O Espejo…

文献索引:Cherbuliez,E. et al. Helvetica Chimica Acta, 1967 , vol. 50, p. 331 - 346

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被引用次数: 18

摘要

Abstract 3-Aminopropanol reacts with aryl (or aralkyl or alkyl) isothiocyanates R [BOND] N [DOUBLE BOND] C [DOUBLE BOND] S to yield the corresponding thio-ureas R [BOND] NH [BOND] CS [BOND] NH [BOND](CH 2) 3 OH which, refluxed with hydrochloric acid, are cyclized by elimination of water. The cyclization products are identical with the hydrothiazines resulting by elimination of sulfate or phosphate from the sulfuric or ...