Journal of the American Chemical Society

Stereospecific palladium-catalyzed coupling reactions of vinyl iodides with acetylenic tin reagents

JK Stille, JH Simpson

文献索引：Stille,J.K.; Simpson,J.H. Journal of the American Chemical Society, 1987 , vol. 109, p. 2138

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被引用次数: 251

摘要

Abstract: The palladium-catalyzed coupling of alkenyl iodides with alkynylstannanes takes place under mild conditions, stereospecifically and chemoselectively, to give high yields of conjugated enynes. The reaction of (E)-or (Z)-vinyl iodides with alkynyltrimethylstannanes in the presence of catalytic amounts of bis (acetonitrile)(dichloro) palladium (II) is complete within a few minutes at 22 OC, providing geometrically pure products. The coupling ...