An Efficient Synthesis of 1-Alkyl-2-phenyl-4-quinolones from 2-Halobenzoic Acids

YJ Song, JS Choi, JI Lee

文献索引：Song, Yoon Ju; Choi, Jin Sun; Lee, Jae In Bulletin of the Korean Chemical Society, 2013 , vol. 34, # 10 p. 3117 - 3120

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被引用次数: 4

摘要

1-Methyl-2-phenyl-4-quinolones are naturally occurring alkaloids isolated from the leaves and stems of the plant family Rutaceae. 1 They have drawn considerable interest because of their potent pharmacological activities that include antifungal 1a and antitumor activity, 2 inhibition of acetylcholinesterase (AChE), 3 and antimutagenic effect. 4 Several methods have been developed to synthesize 1-alkyl-2-phenyl-4-quinolones from 2'-substituted ...