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Organic letters

Formal Nucleophilic Substitution of Bromocyclopropanes with Amides en route to Conformationally Constrained β-Amino Acid Derivatives

AR Prosser, JE Banning, M Rubina, M Rubin

文献索引:Organic Letters, , vol. 12, # 18 p. 3968 - 3971

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被引用次数: 32

摘要

... Volume: Page: Digital Object Identifier (DOI). ... Organic Letters. ... a Typical reaction conditions: bromocyclopopane 5a (0.5 mmol), amide 4 (1.0 mmol), powdered KOH (1.75 mmol), 18-crown-6 (0.05 mmol), THF (5 mL) - stirred at 85 °C for 12 h. b ...