Chemistry Letters

Selective hydrogenation of 9-aminoacridine over supported noble metal catalysts.

K Sakanishi, I Mochida, H Okazaki, M Soeda

文献索引：Sakanishi, Kinya; Mochida, Isao; Okazaki, Hiroshi; Soeda, Mahito Chemistry Letters, 1990 , # 2 p. 319 - 322

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被引用次数: 6

摘要

The selective hydrogenation of 9-aminoacridine (1) into 1, 2, 3, 4-tetrahydro-derivative (2) was searched using noble metal catalysts (Pd, Rh, Pt, and Ru) at around 80° C and 60° C atm of H 2. The Pd/Al 2 O 3 catalyst was found most selective to produce 2 in a higher yield of 60% at a conversion of 97%. The hydrogenation pathway of 1 is discussed in comparison with that of acridine.