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Synthesis and biological activity of n-cyanoamidines and derivatives of 2, 4-diaminotriazine

EN Dozorova, NP Solov'eva, VV Chistyakov…

文献索引:Dozorova, E. N.; Solov'eva, N. P.; Chistyakov, V. V.; Shvarts, G. Ya.; Faermark, I. F.; et al. Pharmaceutical Chemistry Journal, 1987 , vol. 21, # 10 p. 712 - 717 Khimiko-Farmatsevticheskii Zhurnal, 1987 , vol. 21, # 10 p. 1187 - 1193

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摘要

Hz (8 i65. 4 ppm) and the vicinal 3JczH6 10.7 Hz (6C 2 165.2 ppm) and 3Jc4H6 i0 Hz (6C~ 166.2 ppm)(data at'80~ as well as the comparison of these data with literature data for striazine [6] give evidence in favor of the presence of a triazine ring. Characteristic of the laC NMR spectrum of compound IVa (recorded at room temperature) is the presence of pronounced broadening of the signals of the C 4 and C~ atoms of the triazine ring, the ...