Organic letters

Efficient syntheses of the unknown quinolino [2, 3-c] cinnolines; synthesis of neocryptolepines

MJ Haddadin, RMB Zerdan, MJ Kurth…

文献索引：Haddadin, Makhluf J.; Zerdan, Raghida M. Bou; Kurth, Mark J.; Fettinger, James C. Organic Letters, 2010 , vol. 12, # 23 p. 5502 - 5505

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被引用次数: 23

摘要

A facile, efficient, three-step protocol for the synthesis of the unknown quinolino[2,3-c]cinnoline 5 is introduced. In addition, a new approach for the preparation of the biologically active neocryptolepines 8 in good overall yields is described. ... Quinolines and their heterofused derivatives represent an interesting class of nitrogen-containing heterocycles that have gained attention due to their broad biological activities including antimalarial, antiparasitic, antifungal, antibacterial, ...