Semisynthetic. BETA.-lactam antibiotics. IV. Synthesis and antibacterial activity of new ureidocephalosporin and ureidocephamycin derivatives containing a catechol …

…, M MATSUMOTO, H OKAZAKI, I MATSUNAGA

文献索引：Ohi; Aoki; Shinozaki; Moro; Kuroki; Noto; Nehashi; Matsumoto; Okazaki; Matsunaga Chemical and pharmaceutical bulletin, 1987 , vol. 35, # 5 p. 1903 - 1909

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被引用次数: 18

摘要

New ureidocephalosporin and ureidocephamycin derivatives containing a catechol moiety or its acetate were prepared and their minimum inhibitory concentration values against various microorganisms were determined. Among these compounds, the ureidocephalosporins (2, 3Aa, 3Ba) and ureidocephamycins (4, 5) carrying a methyl group on the nitrogen atom of the ureido bond showed strong activities against Pseudomonas ...