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Tetrahedron letters

Photoacylations of 2-substituted 1, 4-naphthoquinones: A concise access to biologically active quinonoid compounds

PA Waske, J Mattay, M Oelgemöller

文献索引:Waske, Prashant A.; Mattay, Jochen; Oelgemoeller, Michael Tetrahedron Letters, 2006 , vol. 47, # 8 p. 1329 - 1332

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被引用次数: 16

摘要

Photochemical acylations of 2-substituted-1, 4-naphthoquinones with various aldehydes furnished acylated hydroquinones and acylated quinones in moderate to good combined yields. All reactions are easily performed and open a rapid access to biologically active compounds. For the 2-methyl-1, 4-naphthoquinone/butyraldehyde pair, a novel tri-keto compound has been additionally isolated.