Organic letters

Mild decarboxylative allylation of coumarins

R Jana, R Trivedi, JA Tunge

文献索引：Jana, Ranjan; Trivedi, Rushi; Tunge, Jon A. Organic Letters, 2009 , vol. 11, # 15 p. 3434 - 3436

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被引用次数: 28

摘要

Allyl esters of 3-carboxylcoumarins undergo facile decarboxylative coupling at just 25− 50° C. This represents the first extension of decarboxylative C− C bond-forming reactions to the coupling of aromatics with sp3-hybridized electrophiles. Finally, the same concept can be applied to the sp2− sp3 couplings of pyrones and flavones. Thus, a variety of biologically important heteroaromatics can be readily functionalized without the need for strong bases ...