Steric effects on pyrolysis reactions. Thermal retro-ene reaction of pyrazineethanols

Y Houminer, RA Fenner, HV Secor…

文献索引：Houminer, Yoram; Fenner, Robert A.; Secor, Henry V.; Seeman, Jeffrey I. Journal of Organic Chemistry, 1987 , vol. 52, # 18 p. 3971 - 3974

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被引用次数: 8

摘要

Two series of 2-(2-hydroxy-2-phenylethyl) pyrazines were prepared and subjected to pyrolysis conditions (170 OC/diglyme solution). Series A (4a-e) includes substrates in which alkyl groups are placed on the hydroxyalkyl side chain and series B (5a-f) includes pyrazineethanols in which alkyl groups are placed at C (3) of the pyrazine ring. In all cases, the retro-ene reaction yields quantitatively the respective alkylpyrazines and ...