Improved Pinner reaction with CPME as a solvent

K Watanabe, N Kogoshi, H Miki…

文献索引：Watanabe, Kiyoshi; Kogoshi, Naoto; Miki, Hideaki; Torisawa, Yasuhiro Synthetic Communications, 2009 , vol. 39, # 11 p. 2008 - 2013

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被引用次数: 9

摘要

Operationally simple synthetic procedures are always in demand for modern process research. Particularly, improvement of classical transformations by replacing hazardous reagents with safer ones that are environmentally benign is an immediate task. The Pinner reaction is a standard process that can combine nitriles with a variety of nucleophiles under anhydrous acidic conditions, affording a useful key intermediate salt for agrochemical and medicinal ...