Synthesis of stereoisomerically pube (E)-1, 5-diyn-3-enes and (E)-1-bromo-3-yn-1-enes by diastereoselective palladium-catalyzed cross-coupling reaction of 1- …
Abstract In the stepeospecific palladium-catalyzed cross coupling reaction of 1-alkynylzinc chlorides,(E)-1, 2-dibromoethylene reacts preferentially in the presence of (Z)-1, 2- dibromoethylene. Products of di-or mono-substitution can be obtained according to the ratio of reagents.
