bis-Quinolinium Cyclophanes: 8, 14-diaza-1, 7 (1, 4)-diquinolinacyclotetradecaphane (UCL 1848), a highly potent and selective, nonpeptidic blocker of the apamin- …
…, CR Ganellin, PM Dunn, DH Jenkinson
文献索引：Chen; Galanakis; Ganellin; Dunn; Jenkinson Journal of Medicinal Chemistry, 2000 , vol. 43, # 19 p. 3478 - 3481
Introduction. Small conductance Ca2+-activated K+(SKCa) channels comprise an important subclass of K+ channels. 1-4 They occur in many types of cells, both excitable and inexcitable, and have a variety of physiological roles. 1, 5-9 Functional, binding, and structural data have suggested the existence of subtypes of the SKCa channel. 10-13 In accordance with these observations, three SKCa channel subunits have been identified ...
