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Studies on Reactive Pyridylketones Formed by Weinreb Transformations

V Stockmann, SJ Kaspersen…

文献索引:Stockmann, Vegar; Kaspersen, Svein Jacob; Nicolaisen, Alexander; Fiksdahl, Anne Journal of Heterocyclic Chemistry, 2012 , vol. 49, # 3 p. 613 - 620

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被引用次数: 1

摘要

Abstract A method has been developed to allow the preparation of reactive pure vinylpyridylketones and activated vinylketones, in general, to be used in further reactions, such as cycloadditions. The process is based on the Weinreb's amide transformation and includes a quarternary ammonium intermediate and subsequent elimination. Additionally, based on our previous results on the malonate alkylation of 3-nitropyridines and ...