Synthesis of derivatives of 2-phenylthiazolidine-4-carboxylic acid and a study of their radioprotective properties
…, SV Rogozhin, SM Puchkova, TN Tuzhilkova
文献索引：Pavlova, L. A.; Komarova, T. V.; Davidovich, Yu. A.; Rogozhin, S. V.; Puchkova, S. M.; Tuzhilkova, T. N. Pharmaceutical Chemistry Journal, 1986 , vol. 20, # 9 p. 653 - 658 Khimiko-Farmatsevticheskii Zhurnal, 1986 , vol. 20, # 9 p. 1083 - 1088
The starting product, 2-phenylthiazolidine-4-carboxylic acid, was obtained by reacting benzaldehyde with cysteine [i]. A tert-butyloxycarbonyl group (BOC-group) was selected to protect the NH-function. The literature describes an unsubstituted N-BOC-thiazolidine-4- carboxylic acid which was synthesized by the use of tert-butyloxycarbonylazide in a Schotten-Baumann reaction [9]. We have shown that it is more convenient to introduce a ...
