Lipases A and B from Candida antarctica in the enantioselective acylation of ethyl 3-heteroaryl-3-hydroxypropanoates: aspects on the preparation and …

J Brem, A Liljeblad, C Paizs, MI Toşa, FD Irimie…

文献索引：Brem, Juergen; Liljeblad, Arto; Paizs, Csaba; Tosa, Monica Ioana; Irimie, Florin-Dan; Kanerva, Liisa T. Tetrahedron Asymmetry, 2011 , vol. 22, # 3 p. 315 - 322

全文：HTML全文

被引用次数: 23

摘要

The preparative scale kinetic resolution of racemic ethyl 2-and 3-furyl-and 2-and 3-thienyl-3- hydroxypropanoates has been performed by Candida antarctica lipases A and B with vinyl esters. A study based on the present work together with the literature has been carried out in terms of lipase enantiopreference and substrate structure. We also discuss the excellent behavior of the lipase A in O-acylations of secondary alcohols with respect to ...