Tetrahedron letters

Dearomatisation of 1-and 2-cyanonaphthalene through nucleophilic conjugate addition

CMA Sánchez, MJ Iglesias, FL Ortiz

文献索引：Andujar Sanchez, Carmen M.; Iglesias, Ma Jose; Lopez Ortiz, Fernando Tetrahedron Letters, 2002 , vol. 43, # 14 p. 2565 - 2568

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被引用次数: 13

摘要

Conjugate nucleophilic addition of organolithium compounds to 1-and 2-cyanonaphthalene is described for the first time. The dearomatisation is carried out in the presence of HMPA and leads to functionalised dihydronaphthalenes. The nucleophiles used include simple lithium reagents as well as phosphorus-stabilised anions.