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Microwave-assisted parallel synthesis of benzofuran-2-carboxamide derivatives bearing anti-inflammatory, analgesic and antipyretic agents

YS Xie, D Kumar, VDV Bodduri, PS Tarani, BX Zhao…

文献索引:Xie, Yong-Sheng; Kumar, Deepak; Bodduri, V.D. Vijaykumar; Tarani, P. Srivastava; Zhao, Bao-Xiang; Miao, Jun-Ying; Jang, Kiwan; Shin, Dong-Soo Tetrahedron Letters, 2014 , vol. 55, # 17 p. 2796 - 2800

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被引用次数: 21

摘要

Abstract A series of benzofuran-2-carboxamides of biological and medicinal significance were synthesized by a microwave-assisted one-pot parallel approach via O-alkylation/ Knoevenagel condensation. All the compounds were characterized and assayed for their in vivo anti-inflammatory, analgesic and antipyretic activities. The activity data of all compounds were listed and discussed in detail, among which some derivatives exhibited ...