Synthesis and thromboxane synthetase inhibitory activity of di-or tetrahydrobenzo [b] thiophenecarboxylic acid derivatives

…, K Wachi, H Miyazawa, N Hatakeyama…

文献索引：Amemiya, Yoshiya; Terada, Atsusuke; Wachi, Kazuyuki; Miyazawa, Hachio; Hatakeyama, Naoko; et al. Journal of Medicinal Chemistry, 1989 , vol. 32, # 6 p. 1265 - 1272

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被引用次数: 17

摘要

Medicinal Chemistry Research Laboratories, New Lead Research Laboratories, and Biological Research Laboratories, Sankyo Co., Ltd., Hiromachi, Shinagawa-ku Tokyo 140, Japan. Received May 16, 1988 l-Imidazolylalkyl-substituted di-or tetrahydrobenzo [b] thiophenecarboxylic acid derivatives and related compounds were synthesized from tetrahydrobenzo [b] thiophene derivatives (1 or 4) in order to study the structure-activity ...