Stereochemical aspects of the hypophosphorous acid addition to terephthalic schiff bases. Synthesis of new 1, 4??phenylene??bis??aminomethane??bis??phosphonous …
Abstract Terephthalic Schiff bases react with hypophosphorous acid to form 1, 4-phenylene- bis-N-alkyl-aminomethanephosphonous acids in moderate yields. NMR studies demonstrated that—for several examples—this reaction led to the exclusive formation of only one diastereomeric form. NMR investigation of a chiral salt identified the meso form. In contrast hereto, a corresponding addition of hypophosphorous acid to a chiral Schiff base ...
