Fragmentation behavior of a thiourea??based reagent for protein structure analysis by collision??induced dissociative chemical cross??linking

…, F Dreiocker, CH Ihling, M Schäfer…

文献索引：Mueller, Mathias Q.; Dreiocker, Frank; Ihling, Christian H.; Schaefer, Mathias; Sinz, Andrea Journal of Mass Spectrometry, 2010 , vol. 45, # 8 p. 880 - 891

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被引用次数: 18

摘要

Abstract The fragmentation behavior of a novel thiourea-based cross-linker molecule specifically designed for collision-induced dissociation (CID) MS/MS experiments is described. The development of this cross-linker is part of our ongoing efforts to synthesize novel reagents, which create either characteristic fragment ions or indicative constant neutral losses (CNLs) during tandem mass spectrometry allowing a selective and ...