Tetrahedron letters

Influence of cation complexing solvent additives and functional groups in asymmetric alkylations of esters via lithium enolates

G Helmchen, A Selim, D Dorsch, I Taufer

文献索引：Helmchen, Guenter; Selim, Adel; Dorsch, Dieter; Taufer, Irmtraud Tetrahedron Letters, 1983 , vol. 24, # 31 p. 3213 - 3216

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被引用次数: 43

摘要

Abstract Highly diastereoselective alkylations of propionates of chiral alcohols derived from (+)-camphor are described. It is demonstrated that steric shielding as well as cation complexation are important for stereoselection. The latter effects are in part rationalized on the basis of preferential formation of (Z)-or (E)-lithium enolates.