Structural modifications of benzanilide derivatives, effective potassium channel openers. X.

…, A Coi, FL Fiamingo, I Giorgi, M Leonardi, O Livi…

文献索引：Calderone, Vincenzo; Coi, Alessio; Fiamingo, Francesca Lidia; Giorgi, Irene; Leonardi, Michele; Livi, Oreste; Martelli, Alma; Martinotti, Enrica European Journal of Medicinal Chemistry, 2006 , vol. 41, # 12 p. 1421 - 1429

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被引用次数: 20

摘要

Large-conductance calcium-activated potassium (BK) channels are involved in many fundamental cell functions. Consistently, the ability to activate BK channels by exogenous compounds is considered as a promising pharmacodynamic pattern for the potential treatment of several pathologies. In this perspective, the development of new and selective BK-openers can be considered as an actual field of research. This paper reports the ...