Synthesis of amino acids and related compounds. 29. Synthesis and hypolipidemic activities of 5-thienyl-4-oxazoleacetic acid derivatives

…, S Takabe, S Maeda, K Matsumoto

文献索引：Moriya; Takabe; Maeda; Matsumoto; Takashima; Takeyama Journal of Medicinal Chemistry, 1986 , vol. 29, # 3 p. 333 - 341

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被引用次数: 23

摘要

82 4-FPh 3-thienyl CHZCOOH 85 210-211 1720 1590 C15HloFNO3S 13 31 a Yields of esters were based on the acylamino keto esters of the cyclization reaction which is shown in Scheme I and those of acids were based on the corresponding ethyl oxazoleacetates. bMeasured as a Nujol mull. cAll compounds were analyzed for C, H, N, Br, C1, F, and S and the results were within 0.4% of theory. dBiological results are from single experiments.' ...