Hypervalent Iodine (III) Sulfonate Mediated Synthesis of 2??Arylimidazo [1, 2??a] Pyrimidines in Liquid PEG??400

HT Cheng, RS Hou, HM Wang, IJ Kang…

文献索引：Cheng, Hui-Ting; Hou, Rei-Sheu; Wang, Huey-Min; Kang, Iou-Jiun; Lin, Pei-Ying; Chena, Ling-Ching Journal of the Chinese Chemical Society, 2009 , vol. 56, # 3 p. 632 - 635

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被引用次数: 6

摘要

Abstract PEG-400 [poly (ethylene glycol-400)] is used as a “green” recyclable solvent in the one-pot synthesis of 2-arylimidazo [1, 2-a] pyrimidines by reaction with ketones,[hydroxyl (2, 4-dinitrobenzenesulfonyloxy)-iodo] benzene (HDNIB), and 2-aminopyrimidine. Significant rate enhancements and improved yields have been observed.