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Water??Soluble, Donor–Acceptor Biphenyl Derivatives in the 2??(o??Nitrophenyl) propyl Series: Highly Efficient Two??Photon Uncaging of the Neurotransmitter γ?? …

…, CM Davenport, C Herbivo, D Warther…

文献索引:Donato, Loic; Mourot, Alexandre; Davenport, Christopher M.; Herbivo, Cyril; Warther, David; Leonard, Jeremie; Bolze, Frederic; Nicoud, Jean-Francois; Kramer, Richard H.; Goeldner, Maurice; Specht, Alexandre Angewandte Chemie - International Edition, 2012 , vol. 51, # 8 p. 1840 - 1843

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被引用次数: 63

摘要

By using two-photon (TP)[1] photoreleasable neurotransmitters like glutamate (Glu) or g- aminobutyric acid (GABA), neuronal processes can be activated or inhibited with high temporal and spatial control (with around one micron threedimensional precision) with reduced photodamage to cells or organs, and with deeper penetration of the light beam into living tissue compared to that of UV photoactivation.[2] Whereas TP excitation of ...